Polarize was established in 2018 by Prof. Jan Ardenkjær-Larsen to commercialize the SpinAligner, a polarizer for dissolution Dynamic Nuclear Polarization (dDNP). Our mission is to make hyperpolarized MR a routine method that enables new applications in magnetic resonance.

The SpinAligner is based on a 6.7 T superconducting dry magnet that is cooled by a pulse-tube coldhead and compressor. A closed-cycle, continous helium circulation system cools the sample to less than 1.4 K. Thus, the SpinAligner does not require any liquid helium or nitrogen. Dynamic Nuclear Polarization is achieved by irradiation with 188 GHz microwaves. A broadband NMR spectrometer allows detection of all nuclei with high sensitivity. An efficient dissolution system enables hyperpolarization of samples of a wide range and sizes.

Ardenkjær-Larsen JH, Bowen S, Petersen JR, Rybalko O, Vinding MS, Ullisch M, Nielsen NC. Cryogen-Free dissolution Dynamic Nuclear Polarization polarizer operating at 3.35 T, 6.70 T and 10.1 T. Magnetic Resonance in Medicine. 2019 Mar;81(3):2184-2194. DOI: 10.1002/mrm.27537.